There are logistical problems (page numbering, battery life, power, using text to voice) but they are not insurmountable.
Bigger problems are going to come from getting copies downloaded onto the various devices, but even those are solvable.
Some of my thinking is that the teacher will need to think the pedagogy through carefully. Each of these devices has its own set of distractions and disruptions.
My main question is, if the hard copy option exists, whether the students will learn to, or be encouraged to, use the productivity tools that e-books and e-readers afford the user.
My fear is that one of the hard copies will be the teacher.